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While GLP 1 receptor agonists are widely used for diabetes and weight management, clinicians should exercise extra caution in older adults, who often have complex health profiles. These patients may face higher risk VisualAbstract: Retatrutide reduces body weight by 17.5% in patients with obesity 2 Minute Medicine The rise of Ozempic maker Novo Nordisk to one of the world's most valuable companies 5 Reasons You Aren't Losing Weight on Ozempic GLP 1 receptor agonists were originally developed to treat people with type 2 diabetes. More recently, GLP 1 drugs have been trialled in people with obesity. Three Cochrane reviews have found that three drugs (
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.8 ★★★★★
Based on 2100 reviews
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Product Reviews
★★★★★ 4
Not for gnawers
Size: 11.5 in, Color: Bear
I was hoping this would work for my teenage ACD and save my leather goods from being chewed on.
He gnawed on it quietly I was thrilled. But I had to take it from him within a few minutes. Gnawing apparently equals chewing pieces off.
Not made for chewers or gnawers.
It seemed to be well made, was soft, was actually a fairly good size and didn’t get gross when it got spitty. Just didn’t work out for Captain chaos destructor of all.
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Reviewed in the United States on May 4, 2026
★★★★★ 5
chew proof!
got my lab pit mix one of these for christmas for the past 2 years. it lasted the entire year and he is a heavy chewer. just get him a fresh one for the holidays but it would have lasted longer!! not squeaky :)
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Reviewed in the United States on April 7, 2026
★★★★★ 5
It's tough!
This chew toy has held up well. Yes, the squeaker did succumb eventually. Yes, my dog was able to eventually chew pieces from it. However, it has lasted longer than any other chew toy we have purchased other than the Nylabone type. I even bought several for family members who have dogs.
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Reviewed in the United States on August 26, 2025
★★★★★ 4
A bit heavy, so mind the sizing. Good though.
My dog is a relentless chewing Jock. He's 11 lbs of Chi X and runs and chews until he's exhausted. I got the 6" for him and it's a bit heavy. He already unraveled and ate the string tape, so I braided and knotted it. He likes it when I can get him to chase it. I'd get a 4" if I were to do it again. It's a great well made product that really let's him get a good chew on.
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Reviewed in the United States on May 22, 2026
★★★★★ 5
Pup’s new favorite chew toy!
My son let one of my pups have a corn cob, which my dog enjoyed immensely. However, son got scolded as these can be very dangerous to dogs, and I disappointed my pup by taking it away. I went to Amazon to see if, by chance, a dog toy existed that was a corn cob. And there we found this- the new favorite of MANY chew toys for my medium size aggressive chewers. I bought two, one for each. They enjoyed “tug-a-war” due to the handy rope end. It squeaks. It’s strong and well made. It’s by far their favorite chew toy. I did store them in the fridge prior to giving them and pretended to eat them to make the pups think they were “real”. The package says they are dog toothbrushes, so a good benefit there as well. I’m sure we will be getting these regularly.
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Reviewed in the United States on June 2, 2025
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